Ceramide complex

Ceramides are lipids naturally present in the skin. They are the main component of the stratum corneum of the epidermis. There are several types depending on their location and function in the skin. There are NS ceramides, AS ceramides, NP ceramides, AP ceramides, NH ceramides, AH ceramides... Regarding their roles, some people compare ceramides to a real "cement" for the skin. Indeed, they fill the space between the keratinocytes, these small "bricks" that form the stratum corneum. Ceramides restore the protective barrier function, fight against dehydration, sensitivity and ensure a more youthful appearance (firm and plump, reduced wrinkles and fine lines). Ceramides therefore have moisturizing, restorative (restoration of the lipid layer of the epidermis) and anti-aging properties. However, the quality and quantity of ceramides decrease with age. As a result, the skin barrier is damaged. This is why it is important to supplement these ceramides through cosmetic products.

Its mode of action

Ceramides have different modes of action:

Ceramides form a protective film on the skin's surface. This film reduces water loss that causes dehydration. The skin's natural barrier is restored and regenerated to retain moisture and prevent dryness.

In addition, this film blocks the penetration of irritants and allergens, giving ceramides a soothing and anti-irritant effect.

Ceramides also repair the skin barrier. Since they are naturally occurring lipids in the skin, they penetrate the skin and help reform the lipid lamellae.

Ceramides also have anti-aging properties. They reduce the formation of wrinkles and age-related skin dryness.

Use

Ceramides are ideal for dry and sensitive skin, aging skin, or skin prone to atopy. They are commonly found in the formulation of creams, balms, lotions, after-sun care, anti-aging care, and more. Ceramides are also found in hair products. They smooth, protect, moisturize, and strengthen the hair fiber.

It's not uncommon to find phytosphingosine and sphingolipids in ingredient lists. These are precursors to ceramides: they help the upper layers of the skin produce more ceramides, so it can better protect itself.

Security

Fortunately, all skin types can benefit from the benefits of ceramides. Because they're naturally present in the skin, ceramides are suitable for everyone (even the most sensitive skin). Ceramides are also suitable for the eye area. However, ceramides have been found to be particularly effective in improving the skin of atopic-prone skin.

Regarding usage guidelines, it is recommended to test the product before actually using it. Otherwise, the active ingredient is not subject to any restrictions or specific conditions of use (it is a relatively risk-free active ingredient). Finally, ceramides are even more effective when combined with other bioidentical ingredients (fatty acids, glycerin, or cholesterol).

Research

« Ceramides are essential for our life on dry land. Major disturbances to their biosynthesis or transport could be lethal because of an extensive water loss. Even less pronounced alterations of the stratum corneum lipid composition and organization are associated with skin diseases such as atopic dermatitis, psoriasis and ichthyoses and could greatly affect the quality of life of the patients ».

« Formulations containing lipids identical to those in skin and, in particular, some ceramide supplementation could improve disturbed skin conditions ».

Coderch, Luisa, et al. « Ceramides and Skin Function ». American Journal of Clinical Dermatology, vol. 4, n^o 2, 2003, p. 107‑29. Source

At 24h post-application, skin hydration measured for Ceramide cream was significantly greater than that measured for all three of the reference moisturizers tested. Ceramide cream was also found to significantly decrease TEWL (P<0.001) over 24 hours, and was shown to be non-sensitizing to the skin of both adults and children and non-irritating to the skin, eyes and related eye area. »

« Ceramide cream increases skin hydration and improves barrier function which may make it suitable for use on dry skin ».

Spada, Fabrizio, et al. « Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems ». Clinical, Cosmetic and Investigational Dermatology, vol. 11, octobre 2018, p. 491‑97 Source

Ceramides were included in only one of the creams as this allows elucidating any advantage of these lipids in the formulation. (…) GACC cream was shown to give a larger effect on the skin hydration, likely to be because of the presence of ceramides ».

Machado, M., M. R. Bronze, and H. Ribeiro. "New cosmetic emulsions for dry skin." Journal of Cosmetic Dermatology 6.4 (2007): 239-242. Source

« (…) topical application of a lipid mixture, containing free fatty acid, cholesterol, and ceramide in an approximately equimolar ratio, allows normal barrier recover ».

Mao-Qiang, Man, et al. "A natural lipid mixture improves barrier function and hydration in human and murine skin." Journal of the Society of Cosmetic Chemists 47.3 (1996): 157-166. Source

« It is clear that dry skin consisting of low endogenous ceramide is convenient for exogenous ceramide passing ».

Kahraman, Emine, et al. "Recent advances on topical application of ceramides to restore barrier function of skin." Cosmetics 6.3 (2019): 52. Source

« These 12 reports showed that external ceramide-containing preparations can improve dry skin and barrier function in patients with atopic dermatitis ».

Kono, Takeshi, Yoshiki Miyachi, and Makoto Kawashima. "Clinical significance of the water retention and barrier function‐improving capabilities of ceramide‐containing formulations: A qualitative review." The Journal of Dermatology 48.12 (2021): 1807-1816. Source

C Perfect

Ceramide complex

Repairs the skin barrier, keeps it healthy and preserves skin hydration.

Its mode of action

Use

Security

Research

Our products containing this active ingredient