RejuveNAD™ is a novel natural substance that stimulates the endogenous regeneration of NAD+ by activating the NAMPT enzyme. Clinical studies show that this active substance can simultaneously counteract at least 5 characteristics of skin aging: mitochondrial dysfunction, cellular senescence, loss of proteostasis, epigenetic changes, and genomic instability, giving the skin an 8-year younger appearance in just 42 days.