« Glucomannan, a mannose-rich polysaccharide, and gibberellin (…) significantly increases collagen synthesis after topical and oral Aloe vera. Aloe gel not only increased collagen content of the wound but also changed collagen composition (more type III) and increased the degree of collagen cross linking ».
« Exact role is not known, but following the administration of aloe vera gel, an antioxidant protein, metallothionein, is generated in the skin ».
« Aloe vera inhibits the cyclooxygenase pathway and reduces prostaglandin E2 production from arachidonic acid ».
Surjushe, Amar, Resham Vasani, and D. G. Saple. "Aloe vera: a short review." Indian journal of dermatology 53.4 (2008): 163. Source
Feily, A., and M. R. Namazi. "Aloe vera in dermatology: a brief review." Giornale italiano di dermatologia e venereologia: organo ufficiale, Societa italiana di dermatologia e sifilografia 144.1 (2009): 85-91. Source
Vázquez, Beatriz, et al. "Antiinflammatory activity of extracts from Aloe vera gel." Journal of ethnopharmacology 55.1 (1996): 69-75. Source
« All the aloe extracts showed significant antioxidant activity. (…)The three-year-old extract exhibited the strongest radical scavenging activity of 72.19%, which is significantly higher than that of BHT at 70.52% and α-tocopherol at 65.20% ».
Hu, Yun, Juan Xu, and Qiuhui Hu. "Evaluation of antioxidant potential of Aloe vera (Aloe barbadensis Miller) extracts." Journal of agricultural and food chemistry 51.26 (2003): 7788-7791. Source
« Mechanistic studies have shown that the topical and oral treatments with A. vera enhanced the synthesis of glycosaminoglycan components (hyaluronic acid and dermatan sulfate) in the matrix of a healing wound to increase the collagen content of the granulation tissue and the degree of crosslinking».
Haniadka, Raghavendra, et al. "Review on the use of Aloe vera (Aloe) in dermatology." Bioactive Dietary Factors and Plant Extracts in Dermatology (2013): 125-133. Source
Tanno, O., et al. "Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier." British Journal of Dermatology 143.3 (2000): 524-531. source
Visuthikosol, V., et al. "Effect of aloe vera gel to healing of burn wound a clinical and histologic study." J Med Assoc Thai 78.8 (1995): 403-9. Source
« Dry-coated AV gloves that provide for gradual delivery of AV gel to skin produced a uniformly positive outcome of improved skin integrity, decreased appearance of fine wrinkling, and decreased erythema in the management of occupational dry skin and irritant contact dermatitis ».
West, Dennis P., and Ya Fen Zhu. "Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure." American Journal of Infection Control 31.1 (2003): 40-42. Source
